The text on the billboard is in Czech ("A NATOČENÍ ŘAS", "AŽ NA 24H"). The architecture, cobblestone street, and tram tracks strongly suggest a historic city center in the Czech Republic. The "ZÓNA 30" sign is typical for European urban traffic calming. Given the style of the buildings and the language, Prague is the most likely location. I am fairly confident this is in the heart of Prague.

then: guess